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[1]王占彬,达慧娟,郝 敏.循环Tfh、肺神经源性P物质与哮喘病情程度的关系[J].中华肺部疾病杂志,2021,(04):447-449.[doi:10.3877/cma.j.issn.1674-6902.2021.04.009]
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循环Tfh、肺神经源性P物质与哮喘病情程度的关系(PDF)

《中华肺部疾病杂志》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2021年04期
页码:
447-449
栏目:
临床研究
出版日期:
2021-08-20

文章信息/Info

Title:
-
作者:
王占彬1; 达慧娟2; 郝 敏3
102400 北京,北京燕化医院呼吸内科1、综合内科2 102400 北京,北京朝阳医院呼吸与危重症医学科3
Author(s):
-
关键词:
支气管哮喘;  循环滤泡辅助性T细胞;  肺神经源性P物质
Keywords:
-
分类号:
R563
DOI:
10.3877/cma.j.issn.1674-6902.2021.04.009
摘要:
目的 分析循环滤泡辅助性T细胞(Tfh)、肺神经源性P物质(SP)与哮喘病情程度的关系。方法 选取2019年1月至2021年1月医院收治的67例老年哮喘患者,根据病情严重程度分为轻度组23例,中度组25例和重度组19例,比较3组患者外周血循环Tfh、肺神经源性SP水平,比较重度患者与轻中度患者临床特征,采用Logistic回归分析法分析外周血循环Tfh、肺神经源性SP水平与老年哮喘患者病情严重程度的关系。结果 重度和中度患者外周血循环Tfh、肺神经源性SP水平均高于轻度患者(P<0.05),且重度患者外周血循环Tfh、肺神经源性SP水平均高于中度患者(P<0.05); 重度患者合并慢性阻塞性肺疾病、接触有害气体构成比与轻中度患者比较,差异均有统计学意义(P<0.05); Logistic多因素回归分析显示外周血循环Tfh、肺神经源性SP、既往接触有害气体均是老年重度哮喘的独立危险因素(OR=3.501,3.228,2.977,P<0.05)。结论 外周血循环Tfh、肺神经源性SP水平与哮喘患者病情严重程度有关,且二者均为老年重度哮喘患者的危险因素。
Abstract:
-

参考文献/References:

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备注/Memo

备注/Memo:
基金项目: 北京市自然科学基金资助项目(2202002)
通信作者: 达慧娟, Email: HF9530@163.com
更新日期/Last Update: 2021-08-20