|本期目录/Table of Contents|

[1]刘利梅,徐卫华,饶晓红.血清颗粒蛋白前体、C反应蛋白在儿童支原体肺炎中检测的临床意义[J].中华肺部疾病杂志,2021,(04):453-455.[doi:10.3877/cma.j.issn.1674-6902.2021.04.011]
点击复制

血清颗粒蛋白前体、C反应蛋白在儿童支原体肺炎中检测的临床意义(PDF)

《中华肺部疾病杂志》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2021年04期
页码:
453-455
栏目:
出版日期:
2021-08-20

文章信息/Info

Title:
-
作者:
刘利梅; 徐卫华; 饶晓红
233000 合肥,安徽省儿童医院
Author(s):
-
关键词:
儿童;  支原体肺炎;  颗粒蛋白前体;  C反应蛋白
Keywords:
-
分类号:
R563
DOI:
10.3877/cma.j.issn.1674-6902.2021.04.011
摘要:
目的 探讨血清颗粒蛋白前体(PGRN)、C反应蛋白(CRP)在儿童支原体肺炎中检测的临床意义。方法 选取2016年6月至2019年6月我院收治的49例支原体肺炎患儿为观察组,47例细菌性肺炎为对照组。比较两组儿童血清PGRN、CRP水平及临床特征,采用Logistic回归分析判定影响儿童支原体肺炎发生的因素。结果 观察组患儿血清PGRN、CRP水平均低于对照组患儿(P<0.05); 观察组患儿反复呼吸道感染构成比与对照组患儿比较,差异均有统计学意义(P<0.05); Logistic多因素回归分析显示血清PGRN、CRP均是影响支气管肺炎发生的独立危险因素(P<0.05)。结论 观察患儿血清PGRN、CRP水平均异常升高,且均低于对照组患儿,血清PGRN、CRP在儿童观察发生发展中具有意义。
Abstract:
-

参考文献/References:

1 温超超, 卢燕鸣. 基于SAT技术分析浦江镇地区儿童肺炎支原体感染的流行病学特点[J/CD]. 中华肺部疾病杂志(电子版), 2020, 13(4): 493-496.
2 Kutty PK, Jain S, Taylor TH, et al. Mycoplasma pneumoniae among children hospitalized with community-acquired pneumonia[J]. Clin Infect Dis, 2019, 68(1): 5-12.
3 Cummiskey AG, Reardon M. Mycoplasma pneumonia: late treatment leading to acute respiratory distress syndrome and renal failure[J]. Eur J Case Rep Intern Med, 2019, 6(2): 1003-1009.
4 Shah SS. Mycoplasma pneumoniae as a cause of community-acquired pneumonia in children[J]. Clin Infect Dis, 2019, 68(1): 13-14.
5 Kumar S, Roy RD, Sethi GR, et al. Mycoplasma pneumoniae infection and asthma in children[J]. Trop Doct, 2019, 49(2): 117-119.
6 Kim AM, Kang S, Park JH, et al. A spatial analysis of geographic variation and factors associated with hospitalization for bacterial pneumonia in Korea[J]. BMC Pulm Med, 2019, 19(1): 45-53.
7 Meyer Sauteur PM, Krautter S, Ambroggio L, et al. Improved diagnostics help to identify clinical features and biomarkers that predict mycoplasma pneumoniae community-acquired pneumonia in children[J]. Clin Infect Dis, 2020, 71(7): 1645-1654.
8 McCurdy S, Keedy K, Lawrence L, et al. Efficacy of delafloxacin versus moxifloxacin against bacterial respiratory pathogens in adults with community-acquired bacterial pneumonia(CABP): microbiology results from the delafloxacin Phase 3 CABP trial[J]. Antimicrob Agents Chemother, 2020, 64(3): 1949-1958.
9 Ma X, Li Y, Liang Y, et al. Development of a DNA microarray assay for rapid detection of fifteen bacterial pathogens in pneumonia[J]. BMC Microbiol, 2020, 20(1): 177-185.
10 葛丽丽, 陈重芬, 宋银森. 咽拭子支原体RNA检测在儿童肺炎支原体肺炎早期诊断中的应用[J]. 中国卫生检验杂志, 2019, 29(24): 3046-3048+3068.
11 Wei F, Jiang Z, Sun H, et al. Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling[J]. PLoS Pathog, 2019, 15(10): 321-328.
12 Pogonowska M, Poniatowski A, Wawrzyniak A, et al. The role of progranulin(PGRN)in the modulation of anti-inflammatory response in asthma[J]. Cent Eur J Immunol, 2019, 44(1): 97-101.
13 Qu F, Liu J, Yang AP, et al. Blood procalcitonin and c-reactive protein in distinguishing between bacterial and mycoplasma community-acquired pneumonia in children[J]. J Biol Regul Homeost Agents, 2020, 34(5): 1739-1744.
14 Chen P, Huang Z, Chen L, et al. The relationships between LncRNA NNT-AS1, CRP, PCT and their interactions and the refractory mycoplasma pneumoniae pneumonia in children[J]. Sci Rep, 2021, 11(1): 2059-2066.
15 宋秀明. 专家诊治肺炎[M]. 上海: 上海科学技术文献出版社, 2012: 112-114.
16 王 娟, 李艳红, 郭秋野. 胸部X线评分与儿童及成人肺炎支原体肺炎临床表现的相关性研究[J/CD]. 中华肺部疾病杂志(电子版), 2019, 12(3): 352-354.
17 Zhou Y, Wang J, Chen W, et al. Impact of viral coinfection and macrolide-resistant mycoplasma infection in children with refractory Mycoplasma pneumoniae pneumonia[J]. BMC Infect Dis, 2020, 20(1): 633-670.
18 Nakanishi M, Nakashima K, Takeshita M, et al. Ability of high-resolution computed tomography to distinguish Mycoplasma pneumoniae pneumonia from other bacterial pneumonia: Significance of lateral bronchial lesions, less air bronchogram, and no peripheral predominance[J]. Respir Investig, 2020, 58(3): 169-176.
19 Simoni C, Camozzi P, Faré PB, et al. Myositis and acute kidney injury in bacterial atypical pneumonia: Systematic literature review[J]. J Infect Public Health, 2020, 13(12): 2020-2024.
20 Cho YJ, Han MS, Kim WS, et al. Correlation between chest radiographic findings and clinical features in hospitalized children with Mycoplasma pneumoniae pneumonia[J]. PLoS One, 2019, 14(8): 463-468.
21 Ding L, Zhao Y, Li X, et al. Early diagnosis and appropriate respiratory support for Mycoplasma pneumoniae pneumonia associated acute respiratory distress syndrome in young and adult patients: a case series from two centers[J]. BMC Infect Dis, 2020, 20(1): 367-373.
22 Kotela A, Wojdasiewicz P, gosz P, et al. Increased serum levels of progranulin(PGRN)in patients with haemophilic arthropathy[J]. Clin Exp Pharmacol Physiol, 2019, 46(4): 373-379.
23 Luo Q, He X, Zheng Y, et al. Elevated progranulin as a novel biomarker to predict poor prognosis in community-acquired pneumonia[J]. J Infect, 2020, 80(2): 167-173.
24 贝丹丹, 程 雁, 王宁玲. 颗粒蛋白前体在小儿ARDS和重症肺炎中的价值研究[J]. 中国妇幼健康研究, 2019, 37(7): 795-798.
25 Li F, Kong S, Xie K, et al. High ratio of C-reactive protein/procalcitonin predicts Mycoplasma pneumoniae infection among adults hospitalized with community acquired pneumonia[J]. Scand J Clin Lab Invest, 2021, 81(1): 65-71.
26 Neeser OL, Vukajlovic T, Felder L, et al. A high C-reactive protein/procalcitonin ratio predicts Mycoplasma pneumoniae infection[J]. Clin Chem Lab Med, 2019, 57(10): 1638-1646.
27 Wang J, Mao J, Chen G, et al. Evaluation on blood coagulation and C-reactive protein level among children with mycoplasma pneumoniae pneumonia by different chest imaging findings[J]. Medicine(Baltimore), 2021, 100(3): 239-246.
28 Huang I, Pranata R, Lim MA, et al. C-reactive protein, procalcitonin, D-dimer, and ferritin in severe coronavirus disease-2019: a meta-analysis[J]. Ther Adv Respir Dis, 2020, 10(1): 98-107.
29 Groeneveld GH, van de Peppel RJ, de Waal MWM, et al. Clinical factors, C-reactive protein point of care test and chest X-ray in patients with pneumonia: A survey in primary care[J]. Eur J Gen Pract, 2019, 25(4): 229-235.

备注/Memo

备注/Memo:
基金项目: 安徽省重点研究和开发计划项目(1804h08020285)
更新日期/Last Update: 2021-08-20