|本期目录/Table of Contents|

[1]钱丹,何佳霖,林昊,等.老年糖尿病患者并发新型冠状病毒肺炎预后及其相关因素分析[J].中华肺部疾病杂志,2022,(01):33-37.[doi:10.3877/cma.j.issn.1674-6902.2022.01.008]
　Qian Dan,He Jialin,Lin Hao,et al.Prognosis and related factors in elderly patients with diabetes mellitus complicated with COVID-19[J].,2022,(01):33-37.[doi:10.3877/cma.j.issn.1674-6902.2022.01.008]
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老年糖尿病患者并发新型冠状病毒肺炎预后及其相关因素分析(PDF)

《中华肺部疾病杂志》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2022年01期
页码:
33-37
栏目:
出版日期:
2022-02-20

文章信息/Info

Title:
Prognosis and related factors in elderly patients with diabetes mellitus complicated with COVID-19
作者:
钱丹1; 何佳霖2; 林昊3; 黄其密2; 刘唯佳2; 赵国策2; 刘玺2; 高梦圆2; 潘鑫涛4; 任成山2
400037 重庆,陆军(第三)军医大学第二附属医院检验科1、消化内科2 610000 成都,四川大学华西临床医学院2019级临床医学八年制(2019181620268)3 200065 上海,上海同济大学附属同济医院发展部4
Author(s):
Qian Dan1;  He Jialin2;  Lin Hao3;  Huang Qimi2;  Liu Weijia2;  Zhao Guoche2;  Liu Xi2;  Gao Mengyuan2;  Pan Xintao4;  Ren Chengshan2.
1Department of Laboratory, The Second Affiliated Hospital, the Third Military Medical University, Chongqing, 400037, China; 2Department of Gastroenterology, The Second Affiliated Hospital, the Third Military Medical University, Chongqing, 400037, China; 3Eight-year-program for Clinical Medicine(2019181620268), West China School of Medicine, Sichuan University, Chengdu 610041, China;?4Development Department of Tongji Hospital，Tongji University, Shanghai 200065, China
关键词:
新型冠状病毒肺炎;  糖尿病;  相关因素;  预后
Keywords:
Corona virus disease 19(COVID-19);  Diabetes mellitus;  Related factors;  Prognosis
分类号:
R512.99,R563.1,R587.1
DOI:
10.3877/cma.j.issn.1674-6902.2022.01.008
摘要:
目的 分析老年糖尿病患者并发新型冠状病毒肺炎(COVID-19)的临床特征及其预后相关因素,为早期防治提供参考依据。方法 以2020年2月4日至2020年4月16日确诊的COVID-19 3 733例中伴有糖尿病的老年患者227例作为分析对象,采集患者一般资料、基础疾病、临床特征、实验室结果等信息,采用SPSS 23.0进行数据描述和分析。结果 227例老年糖尿病患者并发COVID-19被纳入分析,住院期间死亡16例,病死率为7.0%(16/227); 单因素和多因素Logistic回归分析结果提示:肺部疾病、血糖、白细胞、中性粒细胞、肌酐、CKMB和呼吸困难是老年糖尿病并发COVID-19预后危险因素; 采用这些因素预测老年糖尿病并发COVID-19死亡的ROC曲线下面积(AUC)为96.0%(95CI:91.0%～100.0%)。结论 老年人群中,糖尿病患者并发COVID-19的患者其预后风险较高,采用血糖和白细胞等因素预测COVID-19的预后具有临床意义。
Abstract:
Objective To invistigate the clinical characteristics and related mortality factors of elderly patients with diabetes mellitus complicated with COVID-19, and to provide reference for the early prevention and treatment of such patients. Methods A total of 3733 COVID-19 patients confirmed in Hospital, and 227 elderly patients with diabetes were included as the analysis subjects. From medical records extracted general information, basic diseases, clinical characteristics, laboratory results and death of patients and then descripte and analysis through SPSS 23.0. Results 227 elderly patients with diabetes mellitus complicated with COVID-19. Sixteen elderly patients with COVID-19 complicated with diabetes died during hospitalization, with a fatality rate of 7.0%(16/227). Univariate and multivariate logistic regression analysis showed that pulmonary disease, leukocyte, blood sugar, Neutrophils, creatinin, CKMB and dyspnea were correlation factors of prognosis in elderly patients with diabetes complicated with COVID-19; The area under ROC curve for predicting death in elderly patients with diabetes combined with COVID-19 by these factors was 96.0%(95CI:91.0%-100.0%). Conclusion Among the elderly patients, the risk of prognosis with diabetes complicated with COVID-19 is higher, and it possesses higher degree of accuracy to predict the risk of prognosis within these patients by using related factors such as blood sugar and leukocyte.

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备注/Memo

备注/Memo:
基金项目: 重庆市科卫联合资助项目(2020FYYX123)
通信作者: 高梦圆, Email: gmyuan993621@163.com
潘鑫涛, Email: pxtxxz@vip.qq.com
更新日期/Last Update: 2022-02-20