|本期目录/Table of Contents|

[1]杨冰,李霆,乐婷,等.颗粒蛋白前体、AGR联合检测评估慢性阻塞性肺疾病的临床意义[J].中华肺部疾病杂志,2022,(01):47-49.[doi:10.3877/cma.j.issn.1674-6902.2022.01.011]
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颗粒蛋白前体、AGR联合检测评估慢性阻塞性肺疾病的临床意义(PDF)

《中华肺部疾病杂志》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2022年01期
页码:
47-49
栏目:
临床研究
出版日期:
2022-02-20

文章信息/Info

Title:
-
作者:
杨冰1; 李霆2; 乐婷1; 李丽1; 朱路明1
430000 湖北,武汉市第八医院呼吸内科1 430060 湖北,武汉大学人民医院内科2
Author(s):
-
关键词:
急性加重期; 肺疾病; 慢性阻塞性;  外周血颗粒蛋白前体;  白蛋白;  球蛋白
Keywords:
-
分类号:
R563
DOI:
10.3877/cma.j.issn.1674-6902.2022.01.011
摘要:
目的 分析外周血颗粒蛋白前体(PGRN)、血白蛋白与球蛋白比值(AGR)联合检测评估慢性阻塞性肺疾病急性加重期(AECOPD)的临床意义。方法 选择2018年至1月至2019年12月于我院收治的38例COPD患者为COPD组,20例AECOPD患者为AECOPD组; 所有患者均接受外周血PGRN及AGR检查; 分析PGRN联合AGR在评估AECOPD中的价值。结果 AECOPD组患者PGRN、球蛋白水平高于COPD组(P<0.05); 白蛋白及AGRAECOPD组患者低于COPD组(P<0.05); 两组间PGRN、血白蛋白、球蛋白及AGR水平比较差异有统计学意义(P<0.05)。外周血PGRN评估AECOPD的阳性为3.75,阴性为0.41,敏感度为66.00%、特异性为82.40%,Kappa值为48.60%; AGR评估AECOPD的阳性为3.02,阴性为0.53,敏感度为57.10%、特异性为81.10%,Kappa值为39.20%; 外周血PGRN联合AGR评估AECOPD的阳性为21.05,阴性为 0.21,敏感度为80.00%、特异性为92.20%,Kappa值为78.10,外周血PGRN联合AGR评估AECOPD高于外周血PGRN、AGR(P<0.05)。结论 外周血PGRN联合AGR评估AECOPD具较高敏感度及特异性,对评估AECOPD有临床意义。
Abstract:
-

参考文献/References:

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备注/Memo

备注/Memo:
通信作者: 朱路明, Email: 280895704@qq.com
更新日期/Last Update: 2022-02-20