|本期目录/Table of Contents|

[1]刘文龙,王 杰,彭 杰,等.血清PLR与FIB对肺癌术后预后的预测意义[J].中华肺部疾病杂志,2023,(05):682-684.[doi:10.3877/cma.j.issn.1674-6902.2023.05.019]
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血清PLR与FIB对肺癌术后预后的预测意义(PDF)

《中华肺部疾病杂志》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2023年05期
页码:
682-684
栏目:
临床研究
出版日期:
2023-10-20

文章信息/Info

Title:
-
作者:
刘文龙1; 王 杰1; 彭 杰1; 李 纯1; 翟 飞2
432400 孝感,应城市人民医院呼吸与危重症医学科1、胸外科2
Author(s):
-
关键词:
血小板/淋巴细胞比值;  纤维蛋白原;  支气管肺癌;  预后
Keywords:
-
分类号:
R734.2
DOI:
10.3877/cma.j.issn.1674-6902.2023.05.019
摘要:
目的 分析血清血小板/淋巴细胞比值(platelet lymphocyte ratio, PLR)与纤维蛋白原(fibrinogen, FIB)水平变化对肺癌术后预后的预测价值。方法 选取2019年1月至2021年6月我院收治的肺癌患者71例,术前3日检测血清PLR、FIB值; 根据ROC曲线确定界值,分为低PLR组25例与高PLR组46例、低FIB组28例和高FIB组43例; 比较低PLR、FIB组与高PLR、FIB组水平差异; 分析血清PLR、FIB与临床病理特征的关系,判断血清PLR、FIB变化对肺癌术后预后的影响。结果 术前血清PLR、FIB低水平组和高水平组差异有统计学意义(P<0.05); 术后血清PLR值低于术前(P<0.05); 术前血清FIB值高于术后(P<0.05)。血清PLR、FIB低水平组生存率(52.00%、57.14%)高于高水平组(36.96%、39.53%)(P<0.05)。多因素分析显示,TNM Ⅲ期(HR=8.18,95%CI:5.038～20.106)、肿瘤低分化(HR=5.19,95%CI:2.716～10.926)、PLR(HR=3.18,95%CI:2.021～7.906)、FIB(HR=2.31,95%CI:1.210～9.152)是影响肺癌术后预后的危险因素(P<0.05)。结论 血清PLR、FIB水平升高对肺癌术后预后的具有临床意义。
Abstract:
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备注/Memo

备注/Memo:
基金项目: 湖北省卫生计生委科研项目(WJ2021Z0118)
通信作者: 刘文龙, Email: 13797122394@163.com
更新日期/Last Update: 2023-10-20