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《中华肺部疾病杂志》[ISSN:1006-6977/CN:61-1281/TN]

卷:

期数:

2024年03期

页码:

421-425

栏目:

论著

出版日期:

2024-06-25

文章信息/Info

Title:

Clinical features and diagnostic value of procalcitonin and systemic immunoinflammatory index in pregnancy complicated with community-acquired pneumonia

作者:

何 俊¹; 易淑华¹; 陈婷婷¹; 杨 玉¹; 李红雨¹; 谢 飞²; 何 健²

400038 重庆,陆军(第三)军医大学第一附属医院妇产科¹、呼吸与危重症医学科²

Author(s):

He Jun¹;  Yi Shuhua¹;  Chen Tingting¹;  Yang Yu¹;  Li Hongyu¹;  Xie Fei²;  He Jian².

¹Department of Obstetrics and Gynecology, the First Affiliated Hospital of Army Medical University, Chongqing 400038, China; ²Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Army Medical University, Chongqing 400038, China

关键词:

妊娠;  社区获得性肺炎;  降钙素原;  炎症指数;  临床特征

Keywords:

Pregnancy;  Community-acquired pneumonia;  Procalcitonin;  Inflammatory index;  Clinical features

分类号:

R563,R714

DOI:

10.3877/cma.j.issn.1674-6902.2024.03.015

摘要:

目的 分析妊娠并发社区获得性肺炎(community-acquired pneumonia, CAP)临床特征及降钙素原和炎症指数对其诊断意义。方法 选择2020年1月1日至2022年12月31日我院收治的妊娠者11 247例,其中并发社区获得性肺炎102例为观察组,分析临床特征; 选择2022年6月1日至2022年12月31日我院收治的健康妊娠者112例为对照组,采用受试者工作特征曲线下面积(AUC)评价降钙素原(procalcitonin, PCT)和炎症指数(inflammation index, Ⅱ)对妊娠并发社区获得性肺炎的诊断。结果 11 247例中并发社区获得性肺炎102例(0.91%),平均年龄(30.61±5.31)岁,平均孕周(33.60±5.70)周,中孕晚期(28周及以上)91例(89.22%),早产8例(7.84%),低体重儿1例(0.98%); 观察组剖宫产81例(79.41%)高于对照组55例(49.11%)(P<0.001); 两组年龄、BMI比较差异无统计学意义(P>0.05),观察组体温、白细胞、中性粒细胞、血小板、C反应蛋白、降钙素原和炎症指数高于对照组(P<0.05)。AUC分别为体温95%CI:0.652(0.382～0.922)、白细胞95%CI:0.692(0.612～0.772)、中性粒细胞95%CI:0.672(0.623～0.721)、血小板95%CI:0.601(0.515～0.687)、C反应蛋白95%CI:0.653(0.596～0.710)、降钙素原95%CI:0.925(0.878～0.972)和炎症指数95%CI:0.845(0.784～0.906),降钙素原和炎症指数有预测价值。 结论 降钙素原和炎症指数对妊娠并发社区获得性肺炎具有预测意义。

Abstract:

Objective To analyze the clinical features and the diagnostic value of procalcitonin(PCT)and systemic immune-inflammation index(Ⅱ)in pregnancy complicated with community-acquired pneumonia(CAP). Methods From January 1, 2020 to December 31, 2022, pregnant patients admitted to our hospital were the source of the study, including 102 patients with CAP as the observation group, and A total of 112 healthy pregnant women who were hospitalized and gave birth from June 1, 2022 to December 31, 2022 were selected as the control group. The area under the subject working characteristic curve(AUC)was used to evaluate diagnostic value of procalcitonin(PCT)and inflammation index(Ⅱ)for community-acquired pneumonia in pregnancy. Results Among 11247 cases, 102 cases(0.91%)were combined with community-acquired pneumonia, the mean age was(30.61±5.31)years, the mean gestational age was(33.60±5.70)weeks, 91 cases(89.22%)in the third trimester(28 weeks and above), 8 cases(7.84%)in preterm labor, and 1 case(0.98%)in low-weight infant. There were 81 cases of cesarean section in observation group(79.41%)and 55 cases in control group(49.11%)(P<0.001). There was no significant difference in age and BMI between the two groups(P>0.05). The body temperature, white blood cells, neutrophils, platelets, C-reactive protein, procalcitonin and inflammatory index in the observation group were higher than those in the control group(P<0.05). The AUC was 95%CI: 0.652(0.382-0.922)for body temperature, 95%CI: 0.692(0.612-0.772)for leukocytes, 95%CI: 0.672(0.623-0.721)for neutrophils and 95%CI for platelets, respectively: 0.601(0.515-0.687), C-reactive protein 95%CI: 0.653(0.596-0.710), procalcitonin 95%CI: 0.925(0.878-0.972)and inflammatory index 95%CI: 0.845(0.784-0.906), The predictive value of procalcitonin and inflammatory index was high. Conclusion Procalcitonin and systemic immune-inflammation index have good predictive value in pregnancy complicated with CAP.

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备注/Memo

备注/Memo:

基金资助: 重庆市科技局项目(CSTB2022TIAD-KPX0173)
通信作者: 李红雨, Email: leerain1971@163.com

常用功能

更新日期/Last Update: 2024-06-25