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[1]孙志红,庞红艳,王 睿.呼出气体中VOCs联合CT征象诊断非实性肺结节的临床意义[J].中华肺部疾病杂志,2024,(03):442-445.[doi:10.3877/cma.j.issn.1674-6902.2024.03.020 ]
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呼出气体中VOCs联合CT征象诊断非实性肺结节的临床意义(PDF)

《中华肺部疾病杂志》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2024年03期
页码:
442-445
栏目:
临床研究
出版日期:
2024-06-25

文章信息/Info

Title:
-
作者:
孙志红; 庞红艳; 王 睿
061000 沧州,河北沧州市人民医院
Author(s):
-
关键词:
非实性肺结节;  挥发性有机化合物;  CT征象;  诊断价值
Keywords:
-
分类号:
R563,R734.2
DOI:
10.3877/cma.j.issn.1674-6902.2024.03.020
摘要:
目的 分析呼出气体中挥发性有机化合物(volatile organic compounds, VOCs)联合CT征象诊断非实性肺结节的临床意义。方法 收集2020年1月至2022年12月我院收治的47例非实性肺结节患者为对象,根据组织病理学,良性结节32例为对照组,恶性结节15例为观察组。患者给予呼出气体中VOCs、CT检查。分析呼出气体中VOCs、CT征象诊断非实性肺结节的性质。结果 CT征象比较,观察组血管集束征9例(60.00%)、胸膜凹陷征10例(66.67%)、充气支气管征11例(73.33%)高于对照组8例(25.00%),9例(28.12%),12例(37.50%)(P<0.05)。观察组VOCs检出3-甲基戊烷(3-methylpentane)12例(80.00%)、甲苯15例(100.00%)、乙苯14例(93.33%)高于对照组15例(46.88%),24例(75.00%),18例(56.25%)(P<0.05)。呼出气体中VOCs联合CT征象诊断非实性肺结节性质的灵敏度分别为66.67%、73.33%、93.33%,特异度分别为71.88%、75.00%、87.50%,曲线下面积(AUC)分别为0.707、0.744、0.876。结论 呼出气体中VOCs联合CT征象对非实性肺结节性质的诊断具有临床意义。
Abstract:
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备注/Memo

备注/Memo:
基金项目: 河北省卫健委医学科学研究课题计划项目(20200287)
通信作者: 孙志红, Email:sunzhihonghbcz@163.com
更新日期/Last Update: 2024-06-25