|本期目录/Table of Contents|

[1]徐 艳,江秀娟,王 超,等.股直肌剪切波弹性成像对COPD并发肌少症的诊断意义[J].中华肺部疾病杂志,2024,(03):454-457.[doi:10.3877/cma.j.issn.1674-6902.2024.03.023 ]
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股直肌剪切波弹性成像对COPD并发肌少症的诊断意义(PDF)

《中华肺部疾病杂志》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2024年03期
页码:
454-457
栏目:
临床研究
出版日期:
2024-06-25

文章信息/Info

Title:
-
作者:
徐 艳1; 江秀娟2; 王 超1; 江圆满1
621100 四川,川北医学院附属三台医院超声科1、全科医学科2
Author(s):
-
关键词:
肺疾病; 慢性阻塞性;  剪切波弹性成像;  肌少症;  诊断意义
Keywords:
-
分类号:
R563
DOI:
10.3877/cma.j.issn.1674-6902.2024.03.023
摘要:
目的 分析股直肌剪切波弹性成像(shear wave elastography, SWE)对慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)并发肌少症的诊断意义。方法 选择2022年12月至2023年12月我院收治的78例COPD患者,COPD并发肌少症32例为观察组,未并发肌少症46例为对照组,通过股直肌灰阶超声(grayscale ultrasonography, US)和SWE检查确定股直肌厚度(the thickness of the rectus femoris, RFthick)、股直肌横截面积(the cross-sectional area ofthe rectus femoris, RFcsa)和股直肌SWE平均弹性指数(SWEmean); 通过Pearson相关系数分析股直肌数据与COPD临床特征。对比两组股直肌数据,绘制ROC曲线分析股直肌变量对COPD并发肌少症的预测。结果 Pearson相关系数分析显示:RFthick、RFcsa、SWEmean与FEV1、FEV1/FVC、6MWT呈正相关,与mMRC、CAT呈负相关; RFcsa与BMI值呈正相关,SWEmean与5STS、血清抵抗素、TNF-α、GDF15呈负相关(P<0.05)。观察组RFthick[(1.21±0.28)vs.(1.43±0.35)]cm、RFcsa[(3.82±0.38)vs.(4.09±0.41)]cm2和SWEmean[(9.62±2.15)vs.(11.45±3.08)]kPa低于对照组(P<0.05)。多因素Logistic回归分析显示:RFthick(OR=0.028)和SWEmean(OR=0.798)是COPD并发肌少症的影响因素(P<0.05)。ROC曲线结果显示:RFthick、SWEmean的AUC(95%CI)分别是0.735(0.624～0.827)、0.815(0.713～0.893)。结论 与灰阶US相比,SWE不受身高、体质量影响,体现COPD患者的骨骼肌功能; 相较于RFthick,SWEmean对COPD并发肌少症诊断价值,可作为预测COPD并发肌少症具有意义。
Abstract:
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参考文献/References:

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备注/Memo

备注/Memo:
基金项目: 绵阳市卫生健康委员会科研课题(202248)
更新日期/Last Update: 2024-06-25