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[1]曾忠平,张任玲,刘 静,等.恶性肿瘤伴急性呼吸衰竭行有创机械通气危险因素分析[J].中华肺部疾病杂志,2024,(06):991-994.[doi:10.3877/cma.j.issn.1674-6902.2024.06.026
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恶性肿瘤伴急性呼吸衰竭行有创机械通气危险因素分析(PDF)

《中华肺部疾病杂志》[ISSN:1006-6977/CN:61-1281/TN]

卷:
期数:
2024年06期
页码:
991-994
栏目:
临床研究
出版日期:
2024-12-25

文章信息/Info

Title:
-
作者:
曾忠平1; 张任玲1; 刘 静1; 张天莎1; 艾美梅1; 张朋勃2
710100 西安,空军军医大学第一附属医院急诊科1
710100 西安,空军军医大学第一附属医院呼吸与危重症医学科2
Author(s):
-
关键词:
恶性肿瘤;  急性呼吸衰竭;  有创机械通气;  危险因素
Keywords:
-
分类号:
R734.2
DOI:
10.3877/cma.j.issn.1674-6902.2024.06.026
摘要:
目的 分析恶性肿瘤(malignant tumor)伴急性呼吸衰竭(acute respiratory failure)行有创机械通气治疗危险因素,以期为高危患者的管理提供参考。方法 选取2023年1月至2023年12月我院收治的68例恶性肿瘤伴急性呼吸衰竭患者为对象,有创机械通气治疗失败23例为观察组,救治缓解 45例为对照组。采用一般资料调查表、急性生理学及慢性健康状况评分(acute physiology and chronic health evaluation, APACHE Ⅱ)、格拉斯哥昏迷评分量表(Glasgow coma scale, GCS)、临床肺部感染评分量表(clinical pulmonary infection score, CPIS)进行调查,分析有创机械通气治疗失败危险因素。结果 恶性肿瘤68例中有创机械通气救治缓解45例(66.18%),有创机械通气治疗失败23例(33.82%); 观察组有创机械通气时间(24.08±1.18)d长于对照组(16.88±1.05)d; 观察组动脉血氧分压(63.00±20.00)mmHg低于对照组(89.00±21.00)mmHg; 观察组动脉血二氧化碳分压(52.71±15.28)mmHg高于对照组(49.25±13.27)mmHg; 观察组入院时急性生理学及慢性健康状况评分(26.46±1.33)分高于对照组(12.55±4.98)分; 观察组入院时肺部感染评分(10.45±2.11)分高于对照组(5.76±1.43)分; Logistic回归分析显示,有创机械通气时长(OR:1.579,95%CI:1.076～2.319)、APACHE Ⅱ(OR:3.001,95%CI:0.838～10.751)、CPIS(OR:3.859,95%CI:1.475～10.785)是有创机械通气失败的危险因素(P<0.05)。结论 恶性肿瘤伴急性呼吸衰竭有创机械通气时间长、急性生理学及慢性健康状况评分高、临床肺部感染评分高有创机械通气失败风险高,关注高危患者,主动实施针对性救治,提高有创机械通气治疗成功率,改善预后,延长患者生存时间。
Abstract:
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备注/Memo

备注/Memo:
通信作者: 艾美梅, Email: 669255069@qq.com
更新日期/Last Update: 2024-12-25